Ótimo artigo ilustrado sobre a história da lobotomia pré-frontal: The rise & fall of the prefrontal lobotomy

The lobotomy was first performed on humans in the 1890s. About half a century later, it was being touted by some as a miracle cure for mental illness, and its use became widespread; during its heyday in the 1940s and ’50s, the lobotomy was performed on some 40,000 patients in the United States, and on around 10,000 in Western Europe.

Via Neurophilosophy.